Nowadays, an increasing number of microbes broadly distributed in the environment are involved in human and animals diseases, including opportunistic pathogens as etiologic agents of nosocomial infections. These latter microorganisms take advantage of failure in the immune system of vulnerable people, as immune compromised people, to express their pathogenicity.
Furthermore several infectious agents become more and more resistant to the available biocides (antibiotics, antifungal agents, antiparasitic agents…), thus presenting multi-drug resistance (MDR) phenotypes, which are mainly explained by the over expression of MDR efflux pumps.
It is now admitted that, although the intensive use of drugs in human, veterinary, agricultural practices contributes to the development of resistance traits among microorganisms.
The general objective of the project is to survey microorganisms in highly anthropized environments with the aim to discover potential pathogens and their drug resistance mechanisms, and prevent or alert associated disease emerging risks as well as to propose possible control strategies.
PI : Marie-Geneviève DIJOUX-FRANCA (UCBL)
Co-PI : NGUYEN Tien Dat (IMBC-VAST)
NGUYEN Thi Kieu Oanh, USTH PhD student
NGUYEN Thi Luyen, USTH PhD student
NGUYEN Hai Dang, IMBC-VAST
LE Thi Phuong Quynh, INPC-VAST
DUONG Thi Thuy, IET-VAST
HO Tu Cuong, IET-VAST
TRAN Vu Phong, NIHE
NGUYEN Thi Thanh Binh, USTH
PHAM Hoang Nam, USTH PhD student
Sylvie NAZARET, UCBL
Patrick MAVINGUI, UCBL
Claire VALIENTE MORO, UCBL
Dimitri LAVILLETTE, UCBL
Serge MICHALET, UCBL
Guillaume MEIFFREN, CESN, UCBL
Françoise FALSON, UCBL
Roland BARRET, UCBL
Emma ROCHELLE-NEWALL, IRD